Pharmaceutical drugs are frequently impeded by their diminished solubility in physiological conditions, toxicity, physical and chemical volatility, and additional properties. For instance, physical instability can trigger modification of extremely ordered protein structure, causing undesirable processes like precipitation or aggregation.
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Drug delivery polymers have had a crucial role in the advancement of drug delivery technologies by delivering supervised release of therapeutic ingredients in continuous doses over long periods, cyclic dosage, and tunable delivery of both hydrophilic and hydrophobic drugs.
The objective of this study was to prove the significance of GPC in the evaluation of commercially accessible drug delivery materials. In this, six drug delivery polymers, namely Eudragit RS and RL, Eudragit L and S, Ethylcellulose, Cellulose Acetate, Poly(lactic-co-glycolic acid), and a PAMAM dendrimer were examined by standardized Gel Permeation Chromatography (GPC), an analytical provision offered at Jordi Labs.
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