Fluorescent macromolecules and nanoparticles—ranging from natural polymers to engineered nanodiagnostics—are essential in biological, chemical, and medical research. However, the same fluorescence property that makes them interesting also makes them difficult to analyze.
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Basic physical characterization of these materials is as crucial for R&D as for non-fluorescing materials. However, it is more challenging, as fluorescent emissions can interfere with detectors used to measure scattered light.
This article details how Wyatt’s SEC-MALS, DLS, and ELS detectors address fluorescence challenges. It also highlights additional technologies that can handle such samples and presents several case studies.
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This information has been sourced, reviewed and adapted from materials provided by Waters | Wyatt Technology.
For more information on this source, please visit Waters | Wyatt Technology.