May 15 2013
Avid Bioservices, Inc., a wholly owned subsidiary of Peregrine Pharmaceuticals, Inc., today announced that its recent success in qualifying an antibody-dependent, cell-mediated cytotoxicity (ADCC) bioassay will be highlighted in a poster presentation at IBC's 23rd International Intensive Symposium Development, Validation and Maintenance of Biological Assays Conference to be held in Seattle, Washington, May 14-16, 2013.
Avid customized a novel nuclear factor of activated T cells (NFAT) potency assay to evaluate and characterize monoclonal antibodies and with extensive testing yielding positive results, has implemented this as part of its standard portfolio of Quality Control (QC) lot release and stability testing capabilities. The latest bioassay success is another example of the variety of bioassays developed at Avid to characterize the activity and potency of therapeutic proteins, including monoclonal antibodies.
The poster will be on display in the poster and exhibit hall, May 14-15, 2013 at the Grand Hyatt Seattle:
"Customization, Scale-up and Qualification of an Antibody-dependent Cell-mediated Cytotoxicity (ADCC) Bioassay"
Location: Poster Board #7
"This is an important milestone for Avid that allows us to offer simple and robust bioassays that avoid much of the variability seen with classical methods," said Connie Chang, director of Process Science for Avid Bioservices. "This latest bioassay provides greater sensitivity and improved reliability, allowing the client to evaluate process changes more effectively than with traditional ADCC-based bioassays. The assay performance has remained consistent throughout the optimization, qualification and scale-up steps, and now serves as a reliable bioassay to support lot release and stability testing for Phase III clinical trials and commercialization of their well characterized biologic."
For additional information on IBC's Development, Validation and Maintenance of Biological Assays Conference, please visit: http://www.ibclifesciences.com/bioassays/overview.xml