Magritek, a leading provider of compact NMR and MRI instruments, has added fluorine measurement capability to their Spinsolve benchtop NMR spectrometers to meet applications needs in the pharmaceutical industry.
The Magritek Spinsolve benchtop NMR spectrometer
The Magritek Spinsolve™ NMR Spectrometer; a cryogen-free benchtop NMR system, has been designed to provide an upgradable platform for versatile NMR spectroscopy applications. The latest upgrade enables users to perform both fluorine and proton measurements on the same sample without the need for complicated retuning of the probe as may be required in alternative commercial systems.
Fluorine measurements are most useful to users of NMR. The 19F nucleus is one of the most important nuclei for NMR spectroscopy due to its 100% natural abundance and that its NMR sensitivity is extremely high. Organofluorine compounds are in common use in the pharmaceutical industry with fluorine often used as a molecular tag so its quantitative detection is vital in the quality control of manufacturing processes.
The Spinsolve NMR spectrometer can now perform both proton and fluorine experiments without any hardware adjustments making it faster and more cost-effective than other spectrometers with single measurements being made in as short a time as 10 seconds.
Users of the new Spinsolve for Education system may upgrade this 1D proton system to have the 19F imaging as well as 2D proton imaging at a very reasonable cost, an upgrade that may be carried out on site in a matter of minutes.
Magritek's latest applications paper shows examples of both proton and fluorine NMR on the same sample. Examples include 2,2,2-trifluoroethanol and 5-bromo-1,2,3-trifluorobenzene. You can obtain full details of the Spinsolve benchtop NMR spectrometer and the full range of analytical products from Magritek by visiting, www.magritek.com where a PDF of the 19F brochure is also available for download.
About Magritek
Magritek provides complete NMR and MRI solutions and applications for Chemical, Pharmaceutical, Oil and Gas, Food and Construction Industries as well as components and subsystems suitable for Research Laboratories and Academic Education.
Magritek has offices in Aachen, Germany, San Diego, USA, and Wellington, New Zealand and a global network of distributors and agents to support customers. The initial NMR technology and IP used in Magritek products grew out of decades of world-class research by Ampere prize winner Professor Bernhard Bluemich's group at RWTH Aachen University, and Gunther Laukien prize winner Paul Callaghan's team at Massey University and Victoria University of Wellington.