PicoQuant GmbH has expanded the compatibility list of its FLIM and FCS upgrade kit to include the Zeiss LSM 880 confocal laser scanning microscope (CLSM). The upgrade kit is an external addition to the CLSM enhancing its capabilities by the addition of time-resolved techniques such as fluorescence lifetime imaging (FLIM), Fluorescence Correlation Spectroscopy (FCS), or advanced time-resolved Förster Resonance Energy Transfer (FRET) analysis.
PicoQuant's LSM upgrade kit consists of three major parts: picosecond pulsed excitation sources, single photon sensitive detection systems, and Time-Correlated Single Photon Counting (TCSPC) data acquisition hardware.
The turn-key system consists of three major parts: picosecond pulsed excitation sources, single photon sensitive detection systems, and Time-Correlated Single Photon Counting (TCSPC) data acquisition hardware. It is also possible to use the Zeiss LSM 880 BiG.2 detection module for FLIM and FCS measurement. The broad range of laser sources available (from 405 nm to 640 nm), high photon sensitivity, and time resolutions ranging from pico- to microseconds make it possible to analyze all types of commonly used fluorophores. The upgrade kit can even be attached if the AiryScan module of the Zeiss LSM 880 is installed.
PicoQuant's FLIM and FCS upgrade kit is a complete set of instruments that can be adapted to Zeiss LSM's in various configurations. The compact and easy-to-use system extends the capabilities of the LSM towards time-resolved measurements with a resolution down to picoseconds and allows users to perform various analyses on this time scale.
About PicoQuant
PicoQuant is a research and development company in the field of optoelectronics. The company was founded in 1996 and is based in the science and technology park Berlin-Adlershof, Germany. The company is a worldwide leader in the field of single photon counting applications. The product line includes pulsed diode lasers and LEDs, photon counting instrumentation, fluorescence lifetime spectrometers and time-resolved confocal microscopes. PicoQuant employs currently around 60 people. Since April 2008 Sales and Support in North America is handled by PicoQuant Photonics North America Inc.