Thermo Scientific™ Acclaro™ Software for the NanoDrop™ UV-Vis Spectrophotometers and Fluorometers

The NanoDrop™ QC Software by Thermo Scientific™, designed for the NanoDrop™ Ultra^C Spectrophotometer, features auto-ranging pathlengths. Accurately measure the UV-Vis absorbance of chemicals or liquid polymers up to 550 AU without diluting them. It is not necessary to know the sample concentration beforehand.

Utilize Thermo Scientific^TM TQ Analyst^TM software's built-in chemometric algorithms to produce results in a matter of seconds. The software can work with a variety of solutions, including adhesives, lubricants, and dyes. For this reason, it is perfect for production quality control or R&D labs.

Enhance the UV-Vis workflow by using an instrument that provides a PC-control experience or is easy to use, eliminates the need for dilution, and executes chemometric algorithms without the need for extra analysis.

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NanoDrop™ Ultra^C UV-Vis Spectrophotometer

• Ergonomic, standalone design - integrated Android^TM tablet provides seamless data transfer via Ethernet, USB, or wireless, and does away with the need for a separate computer.
• Auto-Blank and Auto-Measure functions — With instant measurements that occur when the pedestal arm is down, the Auto-Blank and Auto-Measure features simplify multi-sample processing. Users can turn these functions ON or OFF with a single selection.
• Includes PC software to operate the device, making it easier to develop methods and storing data on a hard drive or network location.
• There are five distinct pedestal pathlengths to choose from: 1.0, 0.2, 0.1, 0.05, and 0.03 mm.
• Auto-range pathlength technology eliminates the need for dilutions when dealing with highly concentrated samples (equivalent to 550 Abs at 10 mm) due to its broad dynamic range.
• CMOS detectors and xenon flash lamps provide spectral data from 190 to 850 nm.
• For micro-volume pedestal technology, 1 to 2 µL of clean sample is needed.

NanoDrop™ QC Quality Control Software

• Instrument software natively runs chemometric analysis - Chemometric analysis is performed natively by instrument software; users can develop chemometric techniques in TQ Analyst Software and import them into NanoDrop^TM QC Software. After the sample measurement is completed, the component information is displayed in a matter of seconds.
• Thermo Scientific Security Suite is included with the instruments. Computer administrators have the ability to stop users from erasing important data and from changing or removing custom methods.
• Spectra data can be readily handled in various software programs and is exported as .tsv files.

NanoDrop™ Ultra^C Cuvette Port

• Stirring and temperature control are included in the cuvette's position.
• Software for 1 mm, 2 mm, 5 mm, and 10 mm cuvettes is already preprogrammed.

Source: Thermo Fisher Scientific - UV-Vis Spectroscopy

Confidence the Sample is Clean

Common sample contaminants like guanidine or phenol salts can obstruct downstream reactions or artificially increase the apparent sample concentration. Purity ratios alone are, therefore, unable to provide a complete picture of whether the sample is suitable for the research.

Thermo Scientific^TM Acclaro^TM Sample Intelligence Technology can identify several undesirable substances and detect when DNA is contaminating an RNA sample.

Contaminant Detection and Analysis

Acclaro provides a thorough assessment of sample purity and can adjust sample absorbance, enabling users to safely detect, measure, and reduce contaminants. Researchers, scientists, and experts in genetic engineering, microbiology, plant biology, and agriculture can now distinguish between the DNA and RNA of bacteria and plants.

Sample Integrity Insight

When bubbles are found in a sample, the technology instantly alerts users, which could result in imprecise measurements if ignored.

Contaminants Identified

Source: Thermo Fisher Scientific - UV-Vis Spectroscopy

Acclaro Contaminant Software Screen. Software identified RNA contaminating a dsDNA sample and provides a corrected dsDNA concentration. Image Credit: Thermo Fisher Scientific - UV-Vis Spectroscopy

Automated calculation of reaction volumes

Calculating how much sample goes into the downstream reaction can be time-consuming, and deciding on a desired sample concentration is only the first step. To let the software do the math for people, use the pre-installed library of kits or add the own. Depending on the concentration of the sample, the qPCR recipe calculator recommends how to set up the reaction.

Image Credit: Thermo Fisher Scientific - UV-Vis Spectroscopy

Choose kit from the dsDNA Setup page. Image Credit: Thermo Fisher Scientific - UV-Vis Spectroscopy

Software guides you to prepare qPCR reaction. Image Credit: Thermo Fisher Scientific - UV-Vis Spectroscopy

Tools tip walk people through how to read prior table. Image Credit: Thermo Fisher Scientific - UV-Vis Spectroscopy

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Archive Options for All

People can quickly store data in their preferred location, such as the cloud, a network hard drive, or a laboratory information management system (LIMS), by connecting NanoDrop Ultra spectrophotometer or fluorometer to a network.

Export to the Cloud

Export data straight to well-known cloud storage platforms, such as Thermo Fisher Connect, Google Drive, and Microsoft OneDrive.

Direct LIMS Integration

With the aid of an integrated RESTful API, send data straight into the LIMS.

View Data in the Preferred Way

Before exporting, edit and preview the data file's contents to make sure it satisfies any downstream requirements.

Export data in multiple file formats and select the type of data exported. Image Credit: Thermo Fisher Scientific - UV-Vis Spectroscopy 

Preview option lets you see what is the data file will contain. Image Credit: Thermo Fisher Scientific - UV-Vis Spectroscopy

View the Report page prior to printing or export directly to .pdf. Image Credit: Thermo Fisher Scientific - UV-Vis Spectroscopy

Accuracy Beyond Expectations

Thermo Scientific^TM Acclaro^TM Pro Software provides outstanding spectrophotometric accuracy. New versions of the most widely used measurement applications are unlocked from the factory with the bundle purchase, offering an error of ±5% across the absorbance dynamic range.

Accurate High-Concentration Measurements

Obtain absorbance measurements with up to 5% error at levels up to 550 Abs (10 mm equivalent), supporting concentrations up to 400 mg/mL IgG or 18,000 ng/µL ssDNA.

Quick, Dilution-Free Procedure

Measure in triplicate on the pedestal in less than two and a half minutes.

Enhanced Calibration

The factory performs an extra calibration on bundle purchases to guarantee that the instrument operates with remarkable accuracy in Acclaro Pro applications.

Source: Thermo Fisher Scientific - UV-Vis Spectroscopy