Brookhaven Receives Vigabatrin Patent to Prevent Opioid Addiction

Catalyst Pharmaceutical Partners, Inc. (NasdaqCM: CPRX) today announced that the European Patent Office (EPO) granted to Brookhaven Science Associates/Brookhaven National Laboratory (Brookhaven) a European patent for the use of vigabatrin for the prevention of addiction to opioids (e.g., oxycodone, hydrocodone) used in pain management.

By dampening dopamine release and thus, the euphoria associated with opioids, the opioid/vigabatrin combination may lower or prevent addictive liability without adversely affecting pain relief. CPP-109 (vigabatrin, a GABA aminotransferase inhibitor) is Catalyst’s lead compound for the treatment of addiction. Opioid abuse is one of the many substance addiction indications covered under Catalyst’s exclusive worldwide license to Brookhaven’s international and domestic vigabatrin patent portfolio.

Patrick J. McEnany, Catalyst’s Chief Executive Officer, commented, “We are pleased that the EPO has granted this patent. As we reported on November 10, 2009, a team of neuroscientists at The Feinstein Institute for Medical Research at North Shore-Long Island Jewish Health System received a $1.2 million grant from the U.S. Department of Defense to conduct an animal study using vigabatrin in combination with opiates to effectively manage pain while reducing the potential for opiate addiction. This study is currently underway, and we look forward to exploring the development of CPP-109, both here and abroad, to manage the addictive liability associated with the use of opiates for pain management.”