This webinar examines a new, redesigned, high-resolution time-of-flight (TOF) mass spectrometer for gas chromatography-mass spectrometry (GC-MS) analysis. It combines a new TOF analyzer with integrated software that uses all available information to identify compounds in complex mixtures.
This innovative GC-MS system has excellent resolving power (R > 30,000), mass precision (< 1 ppm), and various ionization techniques.
These include classical electron ionization (EI), three types of soft ionization (CI, PI, and FI), and a combination of EI/FI/FD and EI/PI ion sources. The device includes innovative data analysis software employing high-resolution MS, EI, and soft ionization methods to automatically identify analytes in complicated combinations.
The software workflow begins with chromatographic peak deconvolution, followed by database matching, elemental composition determination for the molecular ion, isotope pattern matching, and EI fragment accurate mass analysis to identify the most likely candidates for compounds registered in databases.
This information can also help identify chemicals that are not in the database. Numerous materials will be examined to demonstrate the efficacy of combining our new high-performance GC-MS with our new automated qualitative analysis software.
Key Learning Objectives
- Acquiring knowledge of a new GC-HRMS system
- Exploring an automated process for data analysis
- Using EI and soft ionizing with HRMS to simplify the qualitative analysis
Image Credit: JEOL USA, Inc.
About the Presenter
In 2006, John earned his doctorate in applied chemistry from the Colorado School of Mines, with a focus on mass spectrometry. He then pursued postdoctoral research at the National Renewable Energy Laboratory, studying biodiesel combustion.
In 2008, John joined JEOL USA, Inc. as an MS applications chemist, supporting a wide range of MS product lines, including GC-MS, GCxGC-MS, MALDI-MS, and DART-MS. He was promoted to MS Product Manager in October 2020. Currently residing in the Boston area, John enjoys spending his free time outdoors.